Article
A 6-Mb high-resolution physical and transcription map encompassing the hereditary prostate cancer 1 (HPC1) region.
Genomics - 15 Feb 2000
Carpten J D, Makalowska I, Robbins C M, Scott N, Sood R, Connors T D, Bonner T I, Smith J R, Faruque M U, Stephan D A, Pinkett H, Morgenbesser S D, Su K, Graham C, Gregory S G, Williams H, McDonald L, Baxevanis A D, Klingler K W, Landes G M, Trent J M
Abstract excerpt
Several hereditary disease loci have been genetically mapped to the chromosome 1q24-q31 interval, including the hereditary prostate cancer 1 (HPC1) locus. Here, we report the construction of a 20-Mb yeast artificial chromosome contig and a high-resolution 6-Mb sequence-ready bacterial artificial chromosome (BAC)/P1-derived artificial chromosome (PAC) contig of 1q25 by sequence and computational analysis, STS...
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