Detection of drug resistance mutations as a predictor of subsequent virological failure in patients with HIV-1 viral rebounds of less than 1,000 RNA copies/ml.

Abstract excerpt

In order to evaluate the usefulness of resistance testing after a viral rebound with plasma HIV RNA levels of less than 1,000 copies (c)/ml, genotyping was performed on 39 samples from patients on highly active antiretroviral therapy (HAART) showing a viremia of over 50 c/ml up to a maximum of 1,000 c/ml after at least one undetectable viral load result. Protease and reverse transcriptase (RT) sequences were...

Topics

• Antiretroviral Therapy, Highly Active
• Drug Resistance, Multiple, Viral
• Drug Resistance, Viral
• HIV Infections
• HIV Protease
• HIV Reverse Transcriptase
• HIV-1
• Humans
• Mutation
• RNA, Viral