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Article

Clonal resistance analyses of HIV type-1 after failure of therapy with didanosine, lamivudine and tenofovir.

Antiviral therapy - 1 Jan 2010

Barnas Douglas, Koontz Dianna, Bazmi Holly, Bixby Christian, Jemsek Joseph, Mellors John W

Abstract excerpt

BACKGROUND: The rapid failure of initial therapy with combinations of nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) that exclude zidovudine has not been fully explained by standard virus population analyses of HIV type-1 (HIV-1) drug resistance. We therefore investigated HIV-1 genotype and phenotype at the single genome level in samples from patients on a failing regimen of tenofovir (TNV),...

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Source

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Identifiers

PMID: 20516563
DOI: 10.3851/IMP1539
PMCID: PMC2902251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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