Article
Translocation of Na(+),K(+)-ATPase is induced by Rho small GTPase in renal epithelial cells.
Biochemical and biophysical research communications - 11 Oct 2002
Maeda Akio, Amano Mutsuki, Fukata Yuko, Kaibuchi Kozo
Abstract excerpt
The distribution of transmembrane proteins is considered to be crucial for their activities because these proteins mediate the information coming from outside of cells. A small GTPase Rho participates in many cellular functions through its downstream effectors. In this study, we examined the effects of RhoA on the distribution of Na(+),K(+)-ATPase, one of the transmembrane proteins. In polarized renal epithelium,...
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