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Article

Mechanisms of the proteinuria induced by Rho GTPases.

Kidney international - 1 Jun 2012

Wang Liming, Ellis Mathew J, Gomez Jose A, Eisner William, Fennell Walter, Howell David N, Ruiz Phillip, Fields Timothy A, Spurney Robert F

Abstract excerpt

Podocytes are highly differentiated cells that play an important role in maintaining glomerular filtration barrier integrity; a function regulated by small GTPase proteins of the Rho family. To investigate the role of Rho A in podocyte biology, we created transgenic mice expressing doxycycline-in...

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Identifiers

PMID: 22278020
DOI: 10.1038/ki.2011.472
PMCID: PMC3352980

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22278020-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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