Article
Susceptibility to T cell-mediated injury in immune complex disease is linked to local activation of renin-angiotensin system: the role of NF-AT pathway.
Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2002
Suzuki Yusuke, Gómez-Guerrero Carmen, Shirato Isao, López-Franco Oscar, Hernández-Vargas Purificación, Sanjuán Guillermo, Ruiz-Ortega Marta, Sugaya Takeshi, Okumura Ko, Tomino Yasuhiko, Ra Chisei, Egido Jesús
Abstract excerpt
FcR provides a critical link between ligands and effector cells in immune complex diseases. Emerging evidence reveals that angiotensin (Ang)II exerts a wide variety of cellular effects and contributes to the pathogenesis of inflammatory diseases. In anti-glomerular basement membrane Ab-induced gl...
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