Article

Deficiency of complement C3a and C5a receptors does not prevent angiotensin II–induced hypertension and hypertensive end-organ damage

2023-01-25

Abstract excerpt

<h4> Abstract </h4> Complement activation may drive the pathology of hypertension through its effects on innate and adaptive immune responses, aside from direct effects on tissue integrity. Recently it was suggested that hypertension is a disease characterized by a decreased number of forkhead box protein 3 (Foxp3) + regulatory T cells (Tregs) and that combined deficiency of the anaphylatoxin receptors C3aR (compl...

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Literature Corpus work: 36430e18-5de7-5aa6-8dfb-e434b95d4643
DOI: 10.1101/2023.01.23.23284832

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