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Article

The risk of breast cancer associated with dietary lignans differs by CYP17 genotype in women.

The Journal of nutrition - 1 Oct 2002

McCann Susan E, Moysich Kirsten B, Freudenheim Jo L, Ambrosone Christine B, Shields Peter G

Abstract excerpt

Lignans are plant compounds metabolized in the gut to produce the phytoestrogens enterolactone and enterodiol. Reduced breast cancer risks associated with higher urinary lignan excretion may be related to competitive inhibition of endogenous estrogens. Evidence exists that associations with reproductive risk factors for breast cancer differ according to cytochrome P450c17alpha (CYP17) genotype. Genetic...

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Identifiers

PMID: 12368392
DOI: 10.1093/jn/131.10.3036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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