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Article

Strain background alters mammary gland lesion phenotype in transforming growth factor-alpha transgenic mice.

The American journal of pathology - 1 Oct 2002

Rose-Hellekant Teresa A, Gilchrist Kennedy, Sandgren Eric P

Abstract excerpt

Whey acidic protein (WAP)-transforming growth factor (TGF)-alpha transgenic mice acquire both cancerous and noncancerous mammary lesions. For this study, we evaluated the effect of mouse strain background on the incidence, latency, and histotype of two noncancerous lesions, hyperplastic alveolar nodules (analogous to typical hyperplasias in women), and macrocysts. These lesions display characteristics of...

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Identifiers

PMID: 12368216
DOI: 10.1016/s0002-9440(10)64419-7
PMCID: PMC1867309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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