Article
Mammary tumor phenotypes in wild-type aging female FVB/N mice with pituitary prolactinomas.
Veterinary pathology - 1 Jul 2009
Radaelli E, Arnold A, Papanikolaou A, Garcia-Fernandez R A, Mattiello S, Scanziani E, Cardiff R D
Abstract excerpt
Prolactin-secreting pituitary adenomas are common spontaneous lesions in aging FVB females. Prolactin-secreting pituitary proliferations play a significant role in mouse mammary tumorigenesis generally producing adenosquamous carcinomas. Since genetically engineered FVB mice are frequently used to study mammary tumor biology, we have examined a cohort of 64 aging wild-type FVB/N females to establish the...
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