Article
Alterations in Plasmodium falciparum genotypes during sequential infections suggest the presence of strain specific immunity.
The American journal of tropical medicine and hygiene - 1 Jul 2002
Eisen Damon P, Saul Allan, Fryauff David J, Reeder John C, Coppel Ross L
Abstract excerpt
Many of the asexual stage Plasmodium falciparum proteins that are the targets of host protective responses are markedly polymorphic. The full repertoire of diversity is not defined for any antigen. Most studies have focused on the genes encoding merozoite surface proteins 1 and 2 (MSP1, MSP2). We explored the extent of diversity of some of the less studied merozoite surface antigens and analyzed the degree of...
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