Article
Plasmodium falciparum merozoite surface protein 1 (MSP1): genotyping and humoral responses to allele-specific variants.
Acta tropica - 1 Jan 2002
Ekala Marie-Thérèse, Jouin Hélène, Lekoulou Faustin, Issifou Saadou, Mercereau-Puijalon Odile, Ntoumi Francine
Abstract excerpt
The present study is the first to investigate Plasmodium falciparum merozoite surface protein 1 (MSP1) allele-specific humoral responses in residents of central Africa. In endemic areas, acquired immune responses to malaria are assumed to reflect the need to be infected with a large number of antigenically diverse parasite populations. In the work presented here, the relationship between antibody specificity and...
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