Article
Epsilon 4 allele of apolipoprotein E gene associates with lower blood pressure in young Japanese subjects: the Suita Study.
Journal of hypertension - 1 Oct 2002
Katsuya Tomohiro, Baba Shunroku, Ishikawa Kazuhiko, Mannami Toshifumi, Fu Yuxiao, Inamoto Nozomu, Asai Takashi, Fukuda Masayuki, Higaki Jitsuo, Ogata Jun, Ogihara Toshio
Abstract excerpt
OBJECTIVES: The apolipoprotein epsilon 4 allele (APOE/epsilon 4) increases plasma cholesterol level and the risk for the late onset type of Alzheimer's disease. However, the correlation between hypertension and APOE/epsilon 4 has not yet been clarified. To examine the APOE/epsilon 4 effect in the general population of Japan, we performed a large genetic epidemiological survey (the Suita Study). DESIGN AND...
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