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Article

Reduced susceptibility to collagen-induced arthritis in DBA/1J mice expressing the TSG-6 transgene.

Arthritis and rheumatism - 1 Sept 2002

Mindrescu C, Dias A A M, Olszewski R J, Klein M J, Reis L F L, Wisniewski H-G

Abstract excerpt

OBJECTIVE: Expression of TSG-6 (tumor necrosis factor-stimulated gene 6) is induced by proinflammatory cytokines. This study was undertaken to examine the effects of local expression of TSG-6 in arthritic joints of TSG-6 transgenic mice, in the collagen-induced arthritis (CIA) model. METHODS: We generated transgenic mice that harbored the TSG-6 gene under the control of the T cell-specific lck promoter. Arthritis...

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Identifiers

PMID: 12355494
DOI: 10.1002/art.10503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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