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Article

Gene therapy of arthritis with TCR isolated from the inflamed paw.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2006

Fujio Keishi, Okamoto Akiko, Araki Yasuto, Shoda Hirofumi, Tahara Hiroyuki, Tsuno Nelson H, Takahashi Koki, Kitamura Toshio, Yamamoto Kazuhiko

Abstract excerpt

In recent years, the treatment of autoimmune diseases has been significantly advanced by the use of biological agents. However, some biologics are accompanied with severe side effects, including tuberculosis and other types of infection. There is thus a critical need for nonsystemic and lesion-specific methods of delivering these therapeutic agents. We attempted to treat a mouse model of arthritis by using T...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17114489
DOI: 10.4049/jimmunol.177.11.8140

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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