Article
IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse
19 Oct 2018
Abstract excerpt
Auto-inflammatory syndrome, a condition clinically distinct from rheumatoid arthritis, is characterized by systemic inflammation in tissues such as major joints, skin, and internal organs. Autonomous innate-immune activation is thought to promote this inflammation, but underlying pathological mechanisms have not been clarified nor are treatment strategies established. Here, we newly established a mouse model in...
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