Article
Evaluating the results of genomewide linkage scans of complex traits by locus counting.
American journal of human genetics - 1 Nov 2002
Wiltshire Steven, Cardon Lon R, McCarthy Mark I
Abstract excerpt
The evaluation of results from primary genomewide linkage scans of complex human traits remains an area of importance and considerable debate. Apart from the usual assessment of statistical significance by use of asymptotic and empirical calculations, an additional means of evaluation--based on counting the number of distinct regions showing evidence of linkage--is possible. We have explored the characteristics...
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