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Article

Aurora-A kinase interacting protein (AIP), a novel negative regulator of human Aurora-A kinase.

The Journal of biological chemistry - 22 Nov 2002

Kiat Lim Shen, Hui Kam Man, Gopalan Ganesan

Abstract excerpt

Aurora kinases have evolved as a new family of mitotic centrosome- and microtubule-associated kinases that regulate the structure and function of centrosomes and spindle. One of its members, Aurora-A, is a potential oncogene. Overexpression of Aurora-A is also implicated in defective centrosome duplication and segregation, leading to aneuploidy and tumorigenesis in various cancer cell types. However, the...

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PMID: 12244051
DOI: 10.1074/jbc.M206820200

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AIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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