Article
Functional analysis of cis-regulatory elements controlling initiation and maintenance of early Cdx1 gene expression in the mouse.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2002
Lickert Heiko, Kemler Rolf
Abstract excerpt
Members of the Caudal-related homeobox gene family are implicated in anteroposterior (AP) patterning and posterior axis elongation in mammals. Previously, we found that Caudal-related homeobox gene1 (Cdx1) is directly regulated by the Wnt/beta-catenin signaling pathway, and we identified Wnt/beta-catenin responsive elements in the Cdx1 promoter. Here, we have generated a series of transgenic mouse lines to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
