Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Cdx1 homeodomain protein: an integrator of posterior signaling in the mouse.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Oct 2003

Lohnes David

Abstract excerpt

The vertebrate Cdx genes (Cdx1 Cdx2 and Cdx4 in the mouse) encode homeodomain transcription factors related to the Drosophila caudal gene. The vertebrate Cdx gene products have been implicated in the development of the posterior embryo. In particular, loss- and gain-of-function experiments suggest that Cdx members are direct regulators of Hox genes and likely impart posterior information, in part, through this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Drosophila
Share to Fibroblast Growth Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Homeodomain Proteins

Share to Homozygote

Share to Models, Biological

Share to Multigene Family

Share to Tretinoin

Source

Identifiers

PMID: 14505364
DOI: 10.1002/bies.10340

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Cdx1 homeodomain protein: an integrator of posterior signaling in the mouse.PMID 14505364Read ↗

Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation.Semantic proximity Read ↗

Functional analysis of cis-regulatory elements controlling initiation and maintenance of early Cdx1 gene expression in the mouse.Semantic proximity Read ↗

Origins of Cdx1 regulatory elements suggest roles in vertebrate evolution.Semantic proximity Read ↗

Interactions between Cdx genes and retinoic acid modulate early cardiogenesis.Semantic proximity Read ↗

Regulation of axial elongation by Cdx.Semantic proximity Read ↗

Wnt signaling is a key mediator of Cdx1 expression in vivo.Semantic proximity Read ↗

Concerted involvement of Cdx<i>/</i>Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zoneSemantic proximity Read ↗

Overlapping functions of Cdx1, Cdx2, and Cdx4 in the development of the amphibian Xenopus tropicalis.Semantic proximity Read ↗

Cdx4 is required in the endoderm to localize the pancreas and limit beta-cell number.Semantic proximity Read ↗

Prdm1 acts downstream of a sequential RA, Wnt and Fgf signaling cascade during zebrafish forelimb induction.Semantic proximity Read ↗

Cdx2 regulation of posterior development through non-Hox targets.Semantic proximity Read ↗

Cdx4 is a Cdx2 target gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.