Article
Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation.
Development (Cambridge, England) - 1 May 2002
van den Akker Eric, Forlani Sylvie, Chawengsaksophak Kallayanee, de Graaff Wim, Beck Felix, Meyer Barbara I, Deschamps Jacqueline
Abstract excerpt
Mouse Cdx and Hox genes presumably evolved from genes on a common ancestor cluster involved in anteroposterior patterning. Drosophila caudal (cad) is involved in specifying the posterior end of the early embryo, and is essential for patterning tissues derived from the most caudal segment, the analia. Two of the three mouse Cdx paralogues, Cdx 1 and Cdx2, are expressed early in a Hox-like manner in the three germ...
Topics
- Animals
- Animals, Newborn
- Biological Evolution
- Body Patterning
- CDX2 Transcription Factor
- Digestive System
- Extremities
- Ganglia, Spinal
- Gene Expression Regulation, Developmental
- Genes, Homeobox