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Cooperation between p53 Mutation and High Telomerase Transgenic Expression in Spontaneous Cancer Development

19 Sept 2002

Abstract excerpt

Telomerase reintroduction in adult somatic tissues is envisioned as a way to extend their proliferative capacity. It is still a question, however, whether constitutive telomerase expression in adult tissues impacts the normal aging and spontaneous cancer incidence of an organism. Here, we studied the aging and spontaneous cancer incidence of mice with transgenic telomerase expression in a wide range of adult...

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Identifiers

PMID: 12242304
DOI: 10.1128/mcb.22.20.7291-7301.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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