Article
Fully automated three-dimensional tracking of cancer cells in collagen gels: determination of motility phenotypes at the cellular level.
Cancer research - 15 Sept 2002
Demou Zoe N, McIntire Larry V
Abstract excerpt
We developed a fully automated three-dimensional cell tracking system that quantified the effect of extracellular matrix components on the infiltration and migration of tumor cells. The three-dimensional trajectories of two highly invasive cell lines, the human HT-1080 fibrosarcoma and the human MDA-MB-231 adenocarcinoma, were determined for long-term infiltration in plain or Matrigel-containing collagen type I...
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