Article
A mathematical model of glioblastoma tumor spheroid invasion in a three-dimensional in vitro experiment.
Biophysical journal - 1 Jan 2007
Stein Andrew M, Demuth Tim, Mobley David, Berens Michael, Sander Leonard M
Abstract excerpt
Glioblastoma, the most malignant form of brain cancer, is responsible for 23% of primary brain tumors and has extremely poor outcome. Confounding the clinical management of glioblastomas is the extreme local invasiveness of these cancer cells. The mechanisms that govern invasion are poorly understood. To gain insight into glioblastoma invasion, we conducted experiments on the patterns of growth and dispersion of...
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