Article
Real-time motion analysis reveals cell directionality as an indicator of breast cancer progression.
PloS one - 1 Jan 2013
Weiger Michael C, Vedham Vidya, Stuelten Christina H, Shou Karen, Herrera Mark, Sato Misako, Losert Wolfgang, Parent Carole A
Abstract excerpt
Cancer cells alter their migratory properties during tumor progression to invade surrounding tissues and metastasize to distant sites. However, it remains unclear how migratory behaviors differ between tumor cells of different malignancy and whether these migratory behaviors can be utilized to assess the malignant potential of tumor cells. Here, we analyzed the migratory behaviors of cell lines representing...
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