Article
Polymorphisms in the TNFA promoter region is not associated with palmoplantar pustulosis.
Tissue antigens - 1 Aug 2000
Niizeki H, Naruse T, Hashigucci K, Yokoyama M, Yamasaki Y, Akiya K, Tojo T, Urushibara T, Yamazaki Y, Inoko H, Nishikawa T
Abstract excerpt
Polymorphisms of the 5'-flanking promoter/enhancer region of the TNAFA gene were determined in 80 Japanese patients with pulmoplantar pustulosis (PPP). The 5'-flanking region of the TNFA gene from -1107 to 66 was amplified by polymerase chain reaction (PCR) method. Nucleotide sequencing data from the PCR products revealed that 5 single nucleotide polymorphisms at position 1031, -863, -857, -307 and -237. None of...
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