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Article

Frequency of p12K and p12R alleles of HTLV Type 1 in HAM/TSP patients and in asymptomatic HTLV type 1 carriers.

AIDS research and human retroviruses - 1 Sept 2002

Martins M L, Soares B C, Ribas J G, Thorun G W, Johnson J, Kroon E G, Carneiro-Prioetti A B, Bonjardim C A

Abstract excerpt

HTLV-1 has a complex genome, and contains four open reading frames (ORFs) in the 3' region encoding viral and cellular regulatory proteins. p12 is a small, ORF I-encoded hydrophobic protein, the function of which is not well understood. It has been shown that p12 enhances the E5-transforming ability of bovine papillomavirus; and binds to the 16-kDa subunit of the vacuolar ATPase pump, immature forms of the beta...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia-Lymphoma, Adult T-Cell

Share to Oncogene Proteins, Viral

Share to Paraparesis, Tropical Spastic

Share to Sequence Analysis, DNA

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Share to Viral Regulatory and Accessory Proteins

Source

Identifiers

PMID: 12230932
DOI: 10.1089/088922202760265560

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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