Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association of alpha2-macroglobulin polymorphisms with AD in southern Italy.

Neurology - 10 Sept 2002

Zappia M, Cittadella R, Manna I, Nicoletti G, Andreoli V, Bonavita S, Gambardella A, Quattrone A

Abstract excerpt

The authors investigated the segregation of two polymorphisms of the alpha2-macroglobulin gene (A2M-I/D and A2M-Ile1000Val) in patients with sporadic AD from southern Italy. The A2M-I and A2M-Val1000 alleles were more frequent in cases than in controls, and this effect was independent from the APOE-epsilon4 status as well as from the age at onset of AD. Moreover, subjects carrying the A2M genotype I/I-Val/Val had...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Macroglobulins
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Apolipoproteins E

Share to Gene Frequency

Share to Odds Ratio

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 12221172
DOI: 10.1212/wnl.59.5.756

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association of alpha2-macroglobulin polymorphisms with AD in southern Italy.PMID 12221172Read ↗

Alpha2-macroglobulin polymorphisms in Italian sporadic and familial Alzheimer's disease.Semantic proximity Read ↗

Alpha-2 macroglobulin I1000 V polymorphism in Chinese sporadic Alzheimer's disease and Parkinson's disease.Semantic proximity Read ↗

Influence of Alpha-2-Macroglobulin 5 bp I/D and Ile1000Val polymorphisms on the susceptibility of Alzheimer's disease: a systematic review and meta-analysis of 52 studies.Semantic proximity Read ↗

The alpha2-macroglobulin gene in AD: a population-based study and meta-analysis.Semantic proximity Read ↗

Alpha-2-macroglobulin gene, oxidized low-density lipoprotein receptor-1 locus, and sporadic Alzheimer's disease.Semantic proximity Read ↗

Alpha 2-Macroglobulin Polymorphisms and Susceptibility to Alzheimer’s Disease: A Comprehensive Meta-Analysis Based on 62 StudiesSemantic proximity Read ↗

Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease.Semantic proximity Read ↗

Identical distribution of the alpha 2-macroglobulin pentanucleotide deletion in subjects with Alzheimer disease and controls in a German population.Semantic proximity Read ↗

Lack of association between alpha2-macroglobulin polymorphisms and Alzheimer's disease.Semantic proximity Read ↗

Alpha2-macroglobulin exon 24 (Val-1000-Ile) polymorphism is not associated with late-onset sporadic Alzheimer's dementia in the Hungarian population.Semantic proximity Read ↗

[No evidence for genetic association between alpha-2 macroglobulin I1000V polymorphism and sporadic Alzheimer's disease in two independent Chinese populations].Semantic proximity Read ↗

Human alpha2-macroglobulin: genotype-phenotype relation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.