Article
Alpha-2 macroglobulin I1000 V polymorphism in Chinese sporadic Alzheimer's disease and Parkinson's disease.
Neuroscience letters - 9 Aug 2002
Tang Guomei, Zhang Mingyuan, Xie Huijun, Jiang Sanduo, Wang Zucheng, Xu Lin, Hao Yixin, Lin Dayu, Lan Hekui, Wang Yinyu, Chen Lishan, Ren Daming
Abstract excerpt
Several lines of evidence have revealed some overlapping pathologies in Alzheimer's disease (AD) and Parkinson's disease (PD). Although the alpha-2 macroglobulin gene (A2M) might be a risk factor of these two neurodegenerative diseases, conclusions from different studies have remained conflicting. Here we studied the role of A2M I1000 V polymorphism in both AD and PD in a Chinese Han population. We found that the...
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