Article
Alpha-2-macroglobulin gene, oxidized low-density lipoprotein receptor-1 locus, and sporadic Alzheimer's disease.
Neurobiology of aging - 1 Sept 2009
Colacicco Anna Maria, Solfrizzi Vincenzo, D'Introno Alessia, Capurso Cristiano, Kehoe Patrick G, Seripa Davide, Pilotto Alberto, Santamato Andrea, Capurso Antonio, Panza Francesco
Abstract excerpt
A total sample of 169 AD patients, and 264 age- and sex-matched unrelated caregivers from Apulia, southern Italy, were genotypized for alpha-2-macroglobulin (A2M) Val1000/Ile single-nucleotide polymorphism (SNP) (rs669), apolipoprotein E (APOE), and SNPs (+1073 and +1071) in the oxidized low-density lipoprotein receptor-1 (OLR1) gene on chromosome 12. A2M allele and genotype frequencies were similar between AD...
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