Article
Phenotypical and functional characterization of clinical grade dendritic cells.
Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 Jan 2000
de Vries I Jolanda M, Eggert Andreas A O, Scharenborg Nicole M, Vissers Joost L M, Lesterhuis W Joost, Boerman Otto C, Punt Cornelis J A, Adema Gosse J, Figdor Carl G
Abstract excerpt
Dendritic cells (DC) are the professional antigen presenting cells of the immune system. Therefore, several clinical studies have been initiated in which tumor antigen-loaded DC are used as a vaccine to boost an immune response against malignant tumors in patients with cancer. A prerequisite for DC used in these vaccination studies is not only that they are grown under "Good Manufacturing Practice" but equally...
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