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Article

Day 3 Poly (I:C)-activated dendritic cells generated in CellGro for use in cancer immunotherapy trials are fully comparable to standard Day 5 DCs.

Immunology letters - 1 Jul 2014

Truxova Iva, Pokorna Katerina, Kloudova Kamila, Partlova Simona, Spisek Radek, Fucikova Jitka

Abstract excerpt

BACKGROUND: Dendritic cells (DCs) are professional antigen-presenting cells that are capable of inducing immune responses. DC-based vaccines are normally generated using a standard 5- to 7-day protocol. To shorten the DC-based vaccine production for use in cancer immunotherapy, we have developed a fast DC protocol by comparing standard DCs (Day 5 DCs) and fast DCs (Day 3 DCs). METHODS: We tested the generation of...

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Identifiers

PMID: 24726860
DOI: 10.1016/j.imlet.2014.03.010

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