Article
Mannose-binding lectin-low genotypes are associated with milder systemic and immunological disease expression in primary Sjögren's syndrome.
Rheumatology (Oxford, England) - 1 Jan 2009
Ramos-Casals M, Brito-Zerón P, Soria N, Nardi N, Vargas A, Muñoz S, Bové A, Suárez B, Lozano F
Abstract excerpt
OBJECTIVE: To investigate the association of mannose-binding lectin (MBL)-low genotypes with the clinical and immunological expression of primary SS. METHODS: Eighty-one patients with primary SS who fulfilled the 2002 classification criteria were included in the study. MBL2 polymorphisms were investigated by sequence-based DNA typing of the promoter and exon 1. Genotypes 0/0, 0/XA or XA/XA were considered as...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
