Article
A genome-wide screen reveals evidence for a locus on chromosome 11 influencing variation in LDL cholesterol in the NHLBI Family Heart Study.
Human genetics - 1 Sept 2002
Coon Hilary, Eckfeldt John H, Leppert Mark F, Myers Richard H, Arnett Donna K, Heiss Gerardo, Province Michael A, Hunt Steven C
Abstract excerpt
A genome scan was performed for low-density lipoprotein cholesterol concentration (LDL-C) in white subjects who were ascertained through the NHLBI Family Heart Study (FHS). The NIH Mammalian Genotyping Service (Marshfield, Wis.) genotyped 401 autosomal markers spaced at approximate 10-cM intervals. Additional FHS families were genotyped by the FHS Molecular Laboratory at the University of Utah for 243 markers;...
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