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Article

Evidence for a gene influencing high-density lipoprotein cholesterol on chromosome 4q31.21.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2006

Dastani Zari, Quiogue Leigh, Plaisier Christopher, Engert James C, Marcil Michel, Genest Jacques, Pajukanta Päivi

Abstract excerpt

OBJECTIVE: A low level of plasma high-density lipoprotein cholesterol (HDL-C) is a major risk factor for coronary atherosclerosis. To identify novel genes regulating plasma HDL-C levels, we investigated 13 multigenerational French Canadian families with an average of 12 affected individuals per family for genome-wide signals, which we subsequently fine mapped. METHODS AND RESULTS: We genotyped a total of 362...

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Identifiers

PMID: 16322534
DOI: 10.1161/01.ATV.0000198243.83781.a3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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