Article
Evidence for a gene influencing fasting LDL cholesterol and triglyceride levels on chromosome 21q.
Atherosclerosis - 1 Mar 2005
North Kari E, Miller Michael B, Coon Hilary, Martin Lisa J, Peacock James M, Arnett Donna, Zhang Binbin, Province Michael, Oberman Albert, Blangero John, Almasy Laura, Ellison R Curtis, Heiss Gerardo
Abstract excerpt
High levels of low-density lipoprotein (LDL) cholesterol, low levels of high-density lipoprotein (HDL) cholesterol, and high levels of triglycerides (TG) are strong predictors of cardiovascular disease risk. Motivated by previous evidence for pleiotropy between cholesterol and TG levels, we conducted bivariate linkage analysis of LDL cholesterol and TG concentration among participants of the Hypertension Genetic...
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