Article
Evidence of linkage of familial hypoalphalipoproteinemia to a novel locus on chromosome 11q23.
American journal of human genetics - 1 Jun 2000
Kort E N, Ballinger D G, Ding W, Hunt S C, Bowen B R, Abkevich V, Bulka K, Campbell B, Capener C, Gutin A, Harshman K, McDermott M, Thorne T, Wang H, Wardell B, Wong J, Hopkins P N, Skolnick M, Samuels M
Abstract excerpt
Coronary heart disease (CHD) accounts for half of the 1 million deaths annually ascribed to cardiovascular disease and for almost all of the 1.5 million acute myocardial infarctions. Within families affected by early and apparently heritable CHD, dyslipidemias have a much higher prevalence than in the general population; 20%-30% of early familial CHD has been ascribed to primary hypoalphalipoproteinemia (low...
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