Article
Glucocorticoids modulate transformation by v-Src in a cell-specific manner.
Experimental cell research - 10 Sept 2002
Provenzano Claudia, Alemà Stefano, Falcone Germana
Abstract excerpt
In Balb 3T3 murine fibroblasts infected with retroviruses carrying the v-src oncogene, treatment with the glucocorticoid hormone dexamethasone induces a 10-fold increase in the number of transformed foci and of anchorage-independent colonies. In contrast, in NIH-3T3-infected cells the number of foci and of colonies growing in soft agar is considerably reduced by the addition of the hormone. The effect of...
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