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Article

A talin fragment as an actin trap visualizing actin flow in chemotaxis, endocytosis, and cytokinesis.

Cell motility and the cytoskeleton - 1 Oct 2002

Weber Igor, Niewöhner Jens, Du Aiping, Röhrig Ursula, Gerisch Günther

Abstract excerpt

A C-terminal 63-kDa fragment of talin A from Dictyostelium discoideum forms a slowly dissociating complex with F-actin in vitro. This talin fragment (TalC63) has been tagged with GFP and used as a trap for actin filaments in chemotactic cell movement, endocytosis, and mitotic cell division. TalC63 efficiently sequesters actin filaments in vivo. Its translocation reflects the direction and efficiency of an actin...

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PMID: 12211110
DOI: 10.1002/cm.10065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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