Article
Dictyostelium mutants lacking the cytoskeletal protein coronin are defective in cytokinesis and cell motility.
The Journal of cell biology - 1 Jan 1993
de Hostos E L, Rehfuess C, Bradtke B, Waddell D R, Albrecht R, Murphy J, Gerisch G
Abstract excerpt
Coronin is an actin-binding protein in Dictyostelium discoideum that is enriched at the leading edge of the cells and in projections of the cell surface called crowns. The polypeptide sequence of coronin is distinguished by its similarities to the beta-subunits of trimeric G proteins (E. L. de Ho...
Topics
- Actins
- Animals
- Base Sequence
- Cell Compartmentation
- Cell Division
- Cell Movement
- Chemotaxis
- Cyclic AMP
- Dictyostelium
- Fungal Proteins
- Gene Expression
- Microfilament Proteins
- Molecular Sequence Data
- Mutagenesis, Insertional
- Mutation
- Myosins
- Oligodeoxyribonucleotides
- RNA, Fungal