Article
Association between dopamine transporter gene polymorphism and susceptibility to Parkinson's disease in Japan.
Movement disorders : official journal of the Movement Disorder Society - 1 Jul 2002
Nishimura Masataka, Kaji Ryuji, Ohta Mitsuhiro, Mizuta Ikuko, Kuno Sadako
Abstract excerpt
We studied a polymorphism in the dopamine transporter (DAT) gene in 236 Japanese patients with Parkinson's disease (PD) and compared the results with 220 controls. The 1215A/G genotype of the DAT gene was significantly different between PD patients and controls, suggesting a possible involvement of DAT in genetic susceptibility to PD.
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