Article
Association study for Parkinson's disease and a dopamine transporter gene polymorphism (1215A/G).
European neurology - 1 Jan 2002
Lin Chien-Nan, Liu Hsiu-Chih, Tsai Shih-Jen, Liu Tsung-Yun, Hong Chen-Jee
Abstract excerpt
The dopamine transporter (DAT) may play a role in the pathogenesis of Parkinson's disease (PD) because dopamine-specific neurotoxins are taken into dopaminergic nerve terminals via the DAT. A recent study has demonstrated that a DAT polymorphism in exon 9 (1215A/G) is associated with susceptibility to PD. This finding was not replicated by another study, however. Therefore, the significance of this association...
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