Article
Association of the dopamine transporter gene with Parkinson's disease in Korean patients.
Journal of Korean medical science - 1 Aug 2000
Kim J W, Kim D H, Kim S H, Cha J K
Abstract excerpt
Dopamine transporters (DAT) uptake neurotoxic substances such as 1-methyl-4-phenylpyridinium (MPP+) in the dopaminergic nerve terminals and may confer susceptibility to cytotoxic effects of neurotoxic substance. The association of a variable number tandem repeat polymorphism in the DAT gene with Parkinson's disease (PD) in a Korean population was studied. The 10-copy allele was the most common, accounting for...
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