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Article

DNA structural variation affects complex formation and promoter melting in ribosomal RNA transcription.

Molecular genetics and genomics : MGG - 1 Aug 2002

Marilley M, Radebaugh C A, Geiss G K, Laybourn P J, Paule M R

Abstract excerpt

Eukaryotic ribosomal RNA promoters exhibit an unusual conservation of non-canonical DNA structure (curvature, twist angle and duplex stability) despite a lack of primary sequence conservation. This raises the possibility that rRNA transcription factors might utilize structural anomalies in their sequence recognition process. We have analyzed in detail the interaction of the polymerase I transcription factor...

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Source

Identifiers

PMID: 12207225
DOI: 10.1007/s00438-002-0708-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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