Article
Biophysical analysis of influenza A virus RNA promoter at physiological temperatures.
The Journal of biological chemistry - 1 Jul 2011
Noble Erin, Mathews David H, Chen Jonathan L, Turner Douglas H, Takimoto Toru, Kim Baek
Abstract excerpt
Each segment of the influenza A virus (IAV) genome contains conserved sequences at the 5'- and 3'-terminal ends, which form the promoter region necessary for polymerase binding and initiation of RNA synthesis. Although several models of interaction have been proposed it remains unclear if these two short, partially complementary, and highly conserved sequences can form a stable RNA duplex at physiological...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
