Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Erasure of methylation imprinting of Igf2r during mouse primordial germ‐cell development

20 Mar 2003

Abstract excerpt

During germ cell differentiation in mice, the genome undergoes specific epigenetic modifications. These include demethylation of imprinted genes and subsequent establishment of parental allele-specific methylation. The mouse Igf2r gene is an imprinted gene that shows maternal-specific expression. Maternal-specific methylation of differentially methylated region 2 (DMR2) of this gene may be necessary for its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12658632
DOI: 10.1002/mrd.10264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Erasure of methylation imprinting of Igf2r during mouse primordial germ‐cell developmentPMID 12658632Read ↗

Epigenetic reprogramming in mouse primordial germ cells.Semantic proximity Read ↗

Allele-specific expression of imprinted genes in mouse migratory primordial germ cells.Semantic proximity Read ↗

Methylation dynamics of IG-DMR and Gtl2-DMR during murine embryonic and placental development.Semantic proximity Read ↗

Epigenotype switching of imprintable loci in embryonic germ cells.Semantic proximity Read ↗

Establishment of paternal allele-specific DNA methylation at the imprinted mouse Gtl2 locus.Semantic proximity Read ↗

Adult mice cloned from migrating primordial germ cellsSemantic proximity Read ↗

Timing of establishment of paternal methylation imprints in the mouse.Semantic proximity Read ↗

Epigenetic reprogramming in the porcine germ line.Semantic proximity Read ↗

Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cellsSemantic proximity Read ↗

Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactionsSemantic proximity Read ↗

Biallelic expression of imprinted genes in the mouse germ line: implications for erasure, establishment, and mechanisms of genomic imprinting.Semantic proximity Read ↗

The transgenic IG-DMR sequence of the mouse Dlk1-Dio3 domain acquired imprinted DNA methylation during the post-fertilization periodSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.