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Article

IL-4 is required to prevent filarial nematode development in resistant but not susceptible strains of mice.

International journal for parasitology - 1 Sept 2002

Le Goff Laetitia, Lamb Tracey J, Graham Andrea L, Harcus Yvonne, Allen Judith E

Abstract excerpt

The murine Litomosoides sigmodontis model of filarial infection provides the opportunity to elucidate the immunological mechanisms that determine whether these nematode parasites can establish a successful infection or are rejected by the mammalian host. BALB/c mice are fully susceptible to L. sigmodontis infection and can develop patent infection, with the microfilarial stage circulating in the bloodstream. In...

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Identifiers

PMID: 12204227
DOI: 10.1016/s0020-7519(02)00125-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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