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Article

Susceptibility to Cryptosporidium parvum Infections in Cytokine- and Chemokine-Receptor Knockout Mice

1 Oct 2002

Abstract excerpt

To determine the role of cytokines and a chemokine receptor in the susceptibility to, and outcome of, infection, 4 different knockout mice (IL-4, IL-10, IL-12, and CCR5) were infected with Cryptosporidium parvum and monitored for infection intensity by collection of fecal pellets from individual mice. Because adult immunocompetent mice are refractory to infection, wild-type mice on the same background as the...

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PMID: 12435147
DOI: 10.1645/0022-3395(2002)088[1014:stcpii]2.0.co;2

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