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Article

Targeted "knockdown" of channel expression in vivo with an antisense morpholino oligonucleotide.

Neuroscience - 1 Jan 2002

Brent L J N, Drapeau P

Abstract excerpt

We have examined whether antisense morpholino oligonucleotides (morpholinos) can be used as a tool to suppress or "knockdown" the expression of ion channels during development of the zebrafish. Because the acetylcholine receptor channel is well characterized in zebrafish and is abundant as skeletal muscle is found throughout the body, we sought to knock down its expression as a general test of the feasibility of...

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PMID: 12204196
DOI: 10.1016/s0306-4522(02)00270-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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