Article
Morphants: a new systematic vertebrate functional genomics approach.
Yeast (Chichester, England) - 1 Dec 2000
Ekker S C
Abstract excerpt
The vertebrate genome contains a predicted 50 000-100 000 genes, many of unknown function. The recent development of morpholino-based gene knock-down technology in zebrafish has opened the door to the genome-wide assignment of function based on sequence in a model vertebrate. This review describes technical aspects of morpholino use for functional genomics applications, including the potential for multigene...
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